The injection treatment for Chronic Migraine consists of a series of superficial, low volume injections, performed by a trained Neurologist.
The injection protocol followed is as per the PREEMPT study with several locations targeted over the forehead, temples, back of head, neck and shoulders.
The entire injection procedure requires only 5 to 10 minutes, and most patients find it to be only mildly uncomfortable at worst.
When injection therapy is administered for chronic migraine, side effects are rare. Patients typically are able to drive and otherwise function normally immediately after the injections.
The most common side effects are bruising or swelling at the injection sites or a transient headache of mild intensity that resolves within 24 to 48 hours. On occasion patients may develop flu like symptoms that typically resolve within a day or 2. Transient eye lid droop may occur as a side effect, and some patients may experience transient neck weakness.
Patients may note associated smoothing of forehead wrinkles and some difficulty in voluntarily lifting the eyebrows, when present, these particular effects tend to vanish within 3-4 months.
Because the effects on a developing foetus are unknown, women who are pregnant or intend to soon become pregnant should not receive the therapy.
If you respond to injection therapy, you should expect clinical improvement in the first month after treatment.
Any improvement that occurs tends to persist for a period ranging from 2 weeks to 2 months or more. With subsequent treatments, administered at 12 weekly intervals, some patients experience greater and longer lasting improvements in their headaches.